| A cross-disorder connectome landscape of brain dysconnectivity
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| Nature Reviews Neuroscience, Published online: 24 May 2019; doi:10.1038/s41583-019-0177-6 In this Opinion article, Martijn van den Heuvel and Olaf Sporns examine alterations in structural and functional brain connectivity across brain disorders. They propose a common landscape for such alterations that is based on principles of network organization.
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| New neurons form in the brain into tenth decade of life, even in people with Alzheimer's
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| In a new study from the University of Illinois at Chicago, researchers examining post-mortem brain tissue from people ages 79 to 99 found that new neurons continue to form well into old age. The study provides evidence that this occurs even in people with cognitive impairment and Alzheimer's disease, although neurogenesis is significantly reduced in […]
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New neurons form in the brain into tenth decade of life, even in people with Alzheimer's
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| Ученые нашли способ вылечить рак мозга
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 Недавно группа ученых из Университета Висконсина-Мэдисона и Университета Техаса в Остине провела ряд исследований с использованием рыбы миноги. Данный вид является одним из древнейших на планете, напоминает угрей и населяет реки по всему миру. Но самое главное у нее – рот, полный зубов. Благодаря этому минога паразитирует на других рыбах и питается их кровью. По мнению ученых, именно эта особенность рыбы позволит повысить эффективность лечения рака мозга. Миноги смогут доставлять лекарство прямо в мозг. В этом также поможет особый тип молекул из иммунной системы рыб. Сеть макромолекул миноги составляет большую часть центральной нервной системы. По мнению ученых, именно поэтому рыбам удастся доставить препарат прямо в мозг и повысить эффективность лечения рака, травм головы и инсульта. Подтвердили гипотезу и эксперименты на мышах, больных раком. Дело в том, что у человеческого мозга есть собственный барьер, защищающий от негативных воздействий. К сожалению, этот же барьер не дает полностью пропустить ...
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| New approaches to study the genetics of autism spectrum disorder may lead to new therapies
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| is highly variable disorder, both in its presentation and in its genetics -- hundreds of risk genes have been identified. One key to understanding and ultimately treating ASD is to identify common molecular mechanisms underlying this genetically heterogeneous disorder. Four Canadian researchers presented the results of unique approaches to understand ASD at the 14th Canadian Neuroscience Meeting in Toronto, on May 24, 2019.
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| How single neurons and brain networks support spatial navigation
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 Spatial navigation is an essential cognitive function, which is frequently impaired in patients suffering from neurological and psychiatric disorders. Research groups worldwide have studied the neuronal basis of spatial navigation, and the activity of both individual nerve cells and large cell assemblies in the brain appear to play a crucial role in the process. However, the relationship between the behavior of individual cells and the behavior of large cell networks has for the most part remained unexplored.
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| Hungry for motion: the senses propel predation
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| Nature Neuroscience, Published online: 24 May 2019; doi:10.1038/s41593-019-0412-5 How to know when to hunt or when to lay low? Surprisingly, new research shows that activity in the medial zona incerta specifically initiates predation in the mouse. The medial zona incerta integrates visual motion and tactile stimulation sent from the intermediate superior colliculus to motivate hunting.
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| Teaching the cerebellum about reward
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| Nature Neuroscience, Published online: 24 May 2019; doi:10.1038/s41593-019-0409-0 Selecting the most rewarding action and performing it accurately are two separable brain functions that are thought to rely upon different neural systems. New evidence suggests that the cerebellum could learn to do both.
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